OpenAI launches partnership with U.S. government to advance frontier AI in scientific research

OpenAI has announced a major collaboration with the U.S. Department of Energy, national laboratories, and universities through the Genesis Mission to integrate frontier AI capabilities into American scientific research. The initiative aims to transform AI from a standalone tool into national scientific strategic infrastructure, enabling researchers to explore more ideas, test hypotheses rapidly, and move from discovery to validated results with greater efficiency. OpenAI will provide broad access to its advanced frontier models, technical collaboration, and concentrated resources focused on ambitious scientific challenges. The partnership builds on extensive prior work. Over 1,000 scientists tested frontier models across national laboratories and provided structured feedback on domain-specific problems. OpenAI deployed advanced reasoning models on the Venado supercomputer at Los Alamos National Laboratory to support complex research alongside high-performance computing. The company has also collaborated on bioscience evaluations to study how multimodal AI systems can be safely utilized by scientists in realistic laboratory environments, helping researchers understand both opportunities and risks of increasingly capable systems in consequential research work. The Genesis Mission encompasses large-scale scientific campaigns and aims to establish repeatable methods for applying AI to difficult national challenges. The initiative recognizes that realizing this opportunity requires coordination between government, laboratories, universities, and industry partners, with researchers remaining central to defining questions, selecting methods, and validating results.